quarta-feira, março 31, 2010

O Top Ten da Medicina Intensiva

Na edição atual do Journal of Critical Care estão os artigos mais influentes da medicina intensiva (aqueles com amis citações e que provavelmente tiveram maior repercussão na pesquisa e prática da especialidade).

Vale a leitura desse artigo!

seguem aqui os dez mais para as áreas de sepse e prognóstico.


Most cited articles in critical care medicine by subject
Overall Citation Rank
A. Sepsis/systemic inflammatory response syndrome (no. of times cited)
1. (#6) Tracey, KJ et al. Anti-cachectin TNF monoclonal- antibodies prevent septic shock during lethal bacteremia. Nature 1987. (1983)
2. (#7) Bone, RC et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest 1992. (1838)
3. (#8) Bernard, GR et al. Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 2001. (1827)
4. (#10) Bone, RC et al. American-College of Chest Physicians Society of Critical Care Medicine Consensus Conference— definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 1992. (1724)
5. (#12) Van den Berghe, G et al. Intensive insulin therapy in critically ill patients. N Engl J Med 2001. (1608)
6. (#19) Ziegler, EJ et al. Treatment of gram-negative bacteremia and septic shock with HA-1a human monoclonal-antibody against endotoxin—a randomized, double-blind, placebo- controlled trial. N Engl J Med 1991. (1072)
7. (#22) Angus, DC et al. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med 2001. (1016)
8. (#25) Bone, RC. The pathogenesis of sepsis. Ann Intern Med 1991. (982)
9. (#28) Waage, A et al. The complex pattern of cytokines in serum from patients with meningococcal septic shock— association between interleukin-6, interleukin-1, and fatal outcome. J Exp Med 1989. (892)
10. (#31) Wichterman, KA et al. Sepsis and septic shock—a review of laboratory models and a proposal. J Surg Res 1980. (846)




B. Outcome/benchmarking/prediction model articles (no. of times cited)
1. (#1) Knaus, WA et al. APACHE-II—a severity of disease classification-system. Crit Care Med 1985. (4909)
2. (#4) Baker, SP et al. Injury severity score—method for describing patients with multiple injuries and evaluating emergency care. J Trauma 1974. (2637)
3. (#13) Legall, JR et al. A new simplified acute physiology score (SAPS-II) based on a European North-American multicenter study. JAMA 1993. (1402)
4. (#14) Knaus, WA et al. The APACHE-III prognostic system —risk prediction of hospital mortality for critically ill hospitalized adults. Chest 1991. (1357)
5. (#21) Knaus, WA et al. A controlled trial to improve care for seriously ill hospitalized-patients—the study to understand prognoses and preferences for outcomes and risks of treatments (support). JAMA 1995. (1056)
6. (#26) Fine, MJ et al. A prediction rule to identify low-risk patients with community-acquired pneumonia. N Engl J Med 1997. (965)
7. (#33) Deitch, EA. Multiple organ failure—pathophysiology and potential future therapy. Ann Surg 1992. (793)
8. (#36) Knaus, WA et al. APACHE-acute physiology and chronic health evaluation—a physiologically based classification-system. Crit Care Med 1981. (758)
9. (#38) Vincent, JL et al. The SOFA (sepsis-related organ failure assessment) score to describe organ dysfunction/ failure. Intens Care Med 1996. (735)
10. (#40) Knaus, WA et al. An evaluation of outcome from intensive-care in major medical centers. Ann Intern Med 1986. (715)